Nodule-level localization results for all nodules (3–20-mm diameter). (a) Bar graphs show raw FOMs for each modality combination, and (b) box and whisker plots show the differences of given FOMs for each paired modality comparison. Error bars indicate 95% CIs. Modality combinations are as follows: 1, conventional chest radiography; 2, conventional chest radiography plus DE imaging; 3, tomosynthesis; and 4, tomosynthesis plus DE imaging. MAX_LLF = maximum LLF, MAX_NLF = maximum NLF.