Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Model for the role and regulation of ANO6 to induce diarrhea by Ace stimulation. Ace-mediated activation of RhoA-ROCK influences function of PIP5K, the enzyme that catalyzes the formation of PIP2, which after subsequent interaction to the N-terminal proximal KR motif became the key mechanism to acutely activate ANO6 for Cl− secretion to induce diarrhea.
