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. 2016 Nov 14;291(52):26899–26912. doi: 10.1074/jbc.M116.743443

TABLE 2.

Single channel conductance and open probability values for AgTRPA1 and Δ1–776 AgTRPA1 activated by AITC and heat at a test potential of +60 mV

Stimuli AgTRPA1
Δ1–766 AgTRPA1
AgTRPA1
Δ1–766 AgTRPA1
Conductance, mean ± S.E. n Conductance, mean ± S.E. n Open probability, mean ± S.E. n Open probability, mean ± S.E. n
pS pS
AITC (100 μm) 56 ± 6a 6 87 ± 3a 6 0.53 ± 0.06b 5 0.28 ± 0.05b 6
30 °C 74 ± 6c,d 3 29 ± 2c,e 4 0.45 ± 0.06 4 0.44 ± 0.04 5
40 °C 40 ± 4d 4 50 ± 3e 3 0.53 ± 0.06 4 0.64 ± 0.04 3

a p < 0.01; unpaired t test, two-tailed.

b p < 0.05; unpaired t test, two-tailed.

c–e p < 0.0001, one-way analysis of variance, multiple comparisons.