FIGURE 5.

Mertk^−/− mice displayed progressive retinal degeneration. Representative retinal morphology of 1-, 3-, and 6-month-old Mertk^−/− mice and a 6-month-old WT control are shown. Retinal sections were stained with hematoxylin and eosin (top panels). Scale bars, 50 μm. Retinal sections were immunostained with PNA (green) for cone photoreceptor cells, anti-rhodopsin 1D4 (red) for rod outer segments, and DAPI (blue) for nuclei. Scale bars, 50 μm. WT, wild type; INL, inner nuclear layer; ONL, outer nuclear layer; IS, inner segment; OS, outer segment.