Skip to main content
. 2016 Nov 17;1:17. [Version 1] doi: 10.12688/wellcomeopenres.9917.1

Figure 3. qPCR for CXCL-10, TAP1 and LMP7.

Figure 3.

( A) IL-27 strongly induces CXCL-10 (IP-10) in hepatocytes. Huh7 cells were treated with IL-27 and quantitative PCR for CXCL-10 was performed over time (p value assessed using t test). ( B) mRNA expression of TAP1 and LMP7 in Huh7.5 cells treated with IL-27. Results are from three individual experiments. US, unstimulated; IL, interleukin; CXCL-10, chemokine 10; TAP1, transporter associated with antigen processing 1; LMP-7, low molecular mass polypeptide 7. Significant difference between values of unstimulated (US) and TAP1 were observed only after 6 hrs p=0.0001, and for US Vs LMP7 expression significant values were observed after 24 hrs of stimulation p=0.0132 and significance further increased at 48 hrs to p<0.0001.