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. 2016 Dec 28;11:103–121. doi: 10.2147/DDDT.S115135

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© 2017 Iman et al. This work is published and licensed by Dove Medical Press Limited

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Effects of girinimbine on nuclear morphology, Cyto c release, CP, and MMP.

Notes: (A) Representative images of HT-29 cells stained with Hoechst 33342, Cyto c, CP, and MMP dyes after 24-hour treatment with girinimbine. Magnification: 4×. (B) Representative bar chart indicating the reduction in MMP and the increased CP, TNI, and Cyto c release in treated HT-29 cells after 24 hours. All data are expressed as mean ± SD of three independent experiments (*P<0.05).

Abbreviations: Cyto c, cytochrome c; CP, cell permeability; MMP, mitochondrial membrane potential; TNI, total nuclear intensity; SD, standard deviation.