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. 2016 Dec 28;11:123–131. doi: 10.2147/DDDT.S120399

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© 2017 Jurcevic et al. This work is published and licensed by Dove Medical Press Limited

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Effect of placebo and ponesimod on CD8⁺ T cell subsets.

Notes: Percentage change from baseline (Day 1 pre-dose) in (A) peripheral blood naïve (CD45RA⁺CCR7⁺), (B) effector (CD45RA⁺CCR7⁻), (C) TCM (CD45RA⁻CCR7⁺), and (D) TEM (CD45RA⁻CCR7⁻) CD8⁺ T cells on Day 10 post-dose with placebo or ponesimod. Data are presented as mean with SD. Significance code: *P<0.05, ***P<0.001; t-test placebo vs ponesimod.

Abbreviations: TCM, T-central memory; TEM, T-effector memory; SD, standard deviation; NS, not significant.