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. 2016 Dec 28;11:123–131. doi: 10.2147/DDDT.S120399

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© 2017 Jurcevic et al. This work is published and licensed by Dove Medical Press Limited

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Effect of placebo and ponesimod on NK cells, regulatory T cells, NKT cells, gut-homing T cells, and skin-homing T cells.

Notes: Percentage change from baseline (Day 1 pre-dose) in (A) peripheral NK cells (CD3⁻CD56⁺), (B) regulatory T cells (CD25⁺Foxp3⁺), (C) NKT cells (CD3⁺CD56⁺), (D) gut-homing (CLA⁻integrin β7⁺), and (E) skin-homing (CLA⁺integrin β7⁻) T cells on Day 10 post-dose with placebo or ponesimod. Data are presented as mean with SD. Significance code: **P<0.01, ***P<0.001; t-test placebo vs ponesimod.

Abbreviations: NK, natural killer; NKT, natural killer T memory; SD, standard deviation; NS, not significant.