Fig 4 is incorrectly replaced with Supplemental S4 Fig. The publisher apologizes for the error.
Fig 4. Cell-intrinsic requirement for IL-7Rα, but not TSLPR, signaling in CD8 T cell response to Influenza A.
Lethally irradiated CD45.1 BoyJ mice were reconstituted with (A) 9:1 IL-7Rα449F:BoyJ or (B) 1:1 TSLPR-/-:BoyJ bone-marrow and allowed to recover for 6–8 weeks. Mice were infected with 5HAU of PR8 and the T cell response was analyzed at day 9 post-infection. CD8 T cells were stained for CD45.1 and CD45.2 to identify WT or mutant derived cells. Each population was analyzed for the percent of total CD8 T cells that recognize the NP366–374 tetramer. Data shown is from one representative experiment of two experiments, n = 3–7. *p<0.05 by Student’s t-test.
Please see the correct Fig 4 here.
Supplemental S4 Fig has several errors. The Supplemental S4 Fig lacks changes made during production including the percent of subsets in various flow gates in Panels A and B. Furthermore, the x-axes’ labels titled “NP311-324” should read “NP311-325” in panels A and B. The publisher apologizes for the error.
Please see the correct Supplemental S4 Fig here.
Supporting Information
Lethally irradiated CD45.1 BoyJ mice were reconstituted with (A) 9:1 IL-7Rα449F:BoyJ or (B) 1:1 TSLPR-/-:BoyJ bone-marrow and allowed to recover for 6–8 weeks. Mice were infected with 5HAU of PR8 and the CD4 T cell response was analyzed at day 9 post-infection. CD4 T cells were stained for CD45.1 and CD45.2 to identify WT or mutant derived cells. Each population was analyzed for the percent of CD4 T cells that recognize the NP311–325 tetramer. Irrelevant tetramer staining on CD4 T cells is shown below NP311–325 staining in each panel. Data shown is from one representative experiment of two experiments, n = 3–7. *p<0.05 by Student’s t-test.
(EPS)
Reference
- 1.Plumb AW, Patton DT, Seo JH, Loveday E-K, Jean F, Ziegler SF, et al. (2012) Interleukin-7, but Not Thymic Stromal Lymphopoietin, Plays a Key Role in the T Cell Response to Influenza A Virus. PLoS ONE 7(11): e50199 doi: 10.1371/journal.pone.0050199 [DOI] [PMC free article] [PubMed] [Google Scholar]
Associated Data
This section collects any data citations, data availability statements, or supplementary materials included in this article.
Supplementary Materials
Lethally irradiated CD45.1 BoyJ mice were reconstituted with (A) 9:1 IL-7Rα449F:BoyJ or (B) 1:1 TSLPR-/-:BoyJ bone-marrow and allowed to recover for 6–8 weeks. Mice were infected with 5HAU of PR8 and the CD4 T cell response was analyzed at day 9 post-infection. CD4 T cells were stained for CD45.1 and CD45.2 to identify WT or mutant derived cells. Each population was analyzed for the percent of CD4 T cells that recognize the NP311–325 tetramer. Irrelevant tetramer staining on CD4 T cells is shown below NP311–325 staining in each panel. Data shown is from one representative experiment of two experiments, n = 3–7. *p<0.05 by Student’s t-test.
(EPS)