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. 2017 Jan 3;12(1):e0169215. doi: 10.1371/journal.pone.0169215

Fig 2. The c.-307T>C variant increases OVOL2 promoter activity.

Fig 2

OVOL2 promoter constructs containing either wild type (OVOL2 P WT) or mutant (OVOL2 P c.-307T>C) promoter sequences were transfected into HCEnC-21T cells and the relative luciferase activities of each construct was measured. The OVOL2 P c.-307T>C promoter construct produced significantly higher levels of luminescence compared to the OVOL2 P WT construct. (* p value < 0.05, n = 3, error bars = SEM).