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. 2017 Jan 3;12(1):e0169434. doi: 10.1371/journal.pone.0169434

Fig 1. Interactive Cell Type Diagrams with Parameters.

Fig 1

Parameters driving different types of cell movements or transitions are shown in red. (a) The Two-Cell Model, which incorporates the GoG phenotype, includes two distinct cell types. Invasive cells can only move or die, and proliferating cells can only proliferate or die. The cells switch phenotypes in the presence of hypoxia (P → I) and normoxia (I→P). (b) The Single-Cell Model has a single glioma cell phenotype, which can proliferate, move or die.