Table 6. Comparative Analysis of the Features of Different GBM Models.
Model | CoD motility δ∇ ⋅ (∇I) | HypD motility η∇ ⋅ (I∇B) | GoG | Angiogenesis | Cell Phenotypes (Behavior) | |
---|---|---|---|---|---|---|
Swanson- PI | yes | no | no | no | glioma cells (proliferative and invasive) | |
Swanson- PIHNA | yes | no | no | yes | 1. normoxic cells (proliferative/diffusive) | 2. hypoxic cells (diffusive) |
Dresden | yes | no | yes | yes | 1. mitotic cells (proliferative) | 2. migrating cells (invasive) |
Two-Cell Model | yes | yes | yes | yes | 1. mitotic cells (proliferative) | 2. migrating cells (invasive) |
Single-Cell Model | yes | yes | no | yes | glioma cells (proliferative and invasive) |
The table shows a summary of a few well-known mathematical models and their specific differences. The last two columns display the number of cancer cell phenotypes included in each model as well as the associated behavior of each cell phenotype.