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. 2017 Jan 3;12(1):e0168930. doi: 10.1371/journal.pone.0168930

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© 2017 Goldberg et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 2 — Illustration of 2 different methods to calculate the ventilatory response to hypercapnia (HCVR) using the following 2 variables: Hypercapnia-all and Regression _{(Hypercapnia-all)}. Hypercapnia-all is the change in V_e (ΔV_e) between baseline and the end of the study, divided by the reciprocal change in EtCO₂ (ΔEtCO₂) in the following form: HCVR = ΔV_e/ΔCO₂. Regression _{(Hypercapnia-all)} is the slope of regression line of all measurements.