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Influence of alcohol on DNA hydroxymethylation regardless of iron supplementation. DNA hydroxymethylation was significant decreased in the livers of rats fed an alcohol-containing diet compared to control (P = 0.01). Values are averages and SE (n = 12 per group). C, Lieber-DeCarli control diet (0% calorie from ethanol); A, Lieber-DeCarli alcohol diet (36% calories from ethanol). *Statistically significant at a P < 0.05.
