Fig 1. Aging is accelerated in boss mutant flies.

(A) Lifespan for male and female boss mutant flies. boss mutant flies have shorter lifespan than control flies. Survival was presented by Kaplan Meier curves of control and boss mutant flies. n = 100 for each genotypes. Median survival for control male = 40days, boss mutant males = 13.5 days, control female = 33days, boss mutant females = 9days (Log-rank test, p<0.0001). (B) Analysis of vertical distance climbed in the rapid iterative negative geotaxis assay of boss mutant and control (w) male flies (n = 3 groups; each group contains 10 flies per genotype per time point). Data are means ± SEM, and differences are significant by t-test (*P<0.05).