Table 3. Associations between genotypes and the risk of developing ≥ 2 RP.

			Multivariate analysis			Multivariate analysis
Genotypes	No. of patients	No. of events	HR	95% CI	Pa value	HR	95% CI	Pb value
GSTP1:rs1695
AA	155	27	1			1
GG+GA	110	15	0.796	0.421–1.505	0.483	0.742	0.382–1.442	0.379
SOD2:rs4880
AA	200	33	1			1
GG+AG	65	9	0.888	0.424–1.862	0.753	1.068	0.503–2.268	0.864
GSTA1:rs3957356
CC	196	36	1			1
TT+CT	69	6	0.488	0.205–1.163	0.105	0.499	0.206–1.209	0.123
MTHFR:rs1801131
TT	171	36	1			1
GG+GT	94	6	0.272	0.120–0.656	0.004	0.339	0.137–0.839	0.019
MTHFR:rs1801133
AA	90	15	1			1
GG+GA	175	27	1.241	0.652–2.362	0.510	1.265	0.654–2.450	0.485

P^a values were calculated by Cox proportional model using multivariate analysis.

P^b values were calculated with adjustment for tumor location, stage, chemotherapy and V20.