Table 7. SNPs associated with patient characteristics.
| Outcome | Event (vs non-event) | Gene | SNP ID | Estimated log(OR)1 | Standard error | P-value |
|---|---|---|---|---|---|---|
| AJCC Stage | IIIA/B/C (vs IIA/B)2 | TEK | kgp3874749 | -1.027 | 0.469 | 0.028 |
| ER/PR3 status | Both Negative (vs Any Positive) | FGF2 | kgp11559855 | 1.606 | 0.759 | 0.034 |
| ER/PR/HER2-Neu status | All Three Negative (vs Any Positive) | FGF2 | kgp11559855 | 1.783 | 0.769 | 0.020 |
| Histology | Ductal (vs Other) | VEGFA | rs833068 | 2.349† | 1.068 | 0.028 |
| Histology | Ductal (vs Other) | VEGFA | rs833069 | 2.485† | 1.071 | 0.020 |
1: Estimated natural log of the Odds Ratio (OR) favoring the event over the non-event with each unit increase in the subject’s minor-allele count, as determined by logistic regression. Estimates are adjusted for Race for all outcomes except †Histology, where the 100% prevalence of ductal carcinoma among African Americans precluded a Race adjustment.
2: See Table 1 for the numeric breakdown of AJCC stages.
3: Estrogen Receptor / Progesterone Receptor.