Table 1. Loci and alleles detected by the assays.

Gene	Allele	dbSNP Number	Major Nucleotide Variation	Effect	Enzyme Activity
CYP2C9	*2	rs1799853	c. 430C>T	R144C	Decreased
	*3	rs1057910	c. 1075A>C	I359L	Decreased
	*4	rs56165452	c. 1076T>C	I359T	Decreased
	*5	rs28371686	c. 1080C>G	D360E	Decreased
	*6	rs9332131	c. 818delA	273 Frameshift	None
CYP2C19	*2	rs4244285	c. 681G>A	Splicing defect	None
	*3	rs4986893	c. 636G>A	W212X	None
	*4	rs28399504	c. 1A>G	M1V	None
	*5	rs56337013	c. 1297C>T	R433W	None
	*6	rs72552267	c. 395G>A	R132Q	None
	*7	rs72558186	c. 819+2T>A	Splicing defect	None
	*8	rs41291556	c. 358T>C	W120R	None
	*9	rs28399507	c. 431G>A	R144H	Decreased
	*10	rs6413438	c. 680C>T	P227L	Decreased
	*17	rs12248560	c. -806C>T	Increased expression	Increased
CYP2D6	*2	rs16947, rs1135840	2850C>T, 4180G>C	R296C, S486T	Normal
	*2A	rs1080985, rs16947, rs1135840	-1584C>G, 2850C>T, 4180G>C	R296C, S486T	Normal
	*3	rs35742686	2549delA	259 Frameshift	None
	*4	rs1065852, rs3892097, rs1135840	100C>T, 1846G>A, 4180G>C	P34S, Splicing defect, S486T	None
	*5	n/a	n/a	Gene deletion	None
	*6	rs5030655	1707delT	118 Frameshift	None
	*7	rs5030867	2935A>C	H324P	None
	*8	rs5030865, rs16947, rs1135840	1758G>T, 2850C>T, 4180G>C	G169X, R296C, S486T	None
	*9	rs5030656	2615_2617delAAG	K281del	Decreased
	*10	rs1065852, rs1135840	100C>T, 4180G>C	P34S, S486T	Decreased
	*14	rs5030865, rs16947, rs1135840	1758G>A, 2850C>T, 4180G>C	G169R, R296C, S486T	None
	*17	rs28371706, rs16947, rs1135840	1023C>T, 2850C>T, 4180G>C	T107I, R296C, S486T	Decreased
	*29	rs16947, rs59421388, rs1135840	2850C>T, 3183G>A, 4180G>C	R296C, V338M, S486T	Decreased
	*35	rs769258, rs16947, rs1135840	31G>A, 2850C>T, 4180G>C	V11M, R296C, S486T	Normal
	*36	rs1065852, rs1135840	100C>T, 4180G>C, recombination at exon 9	P34S, S486T, CYP2D6-2D7 hybrid	None
	*41	rs16947, rs28371725, rs1135840	2850C>T, 2988G>A, 4180G>C	R296C, Splicing defect, S486T	Decreased
CYP3A5	*3	rs776746	6986A>G	Splicing defect	None
VKORC1	*2	rs9923231	c. -1639G>A		Decreased