Table 4. Serious adverse events.

Group	CPM (n = 72)	MP (n = 66)
Serious Adverse Events (n)	Sudden death of probable cardio-vascular origin (1)Malignancies (2): one ovarian and one breast cancer, both occurred during the first year of treatment Pericarditis (1)Psychotic episode (1) Rash (1) Hospitalization for surgery (2) Thrombophlebitis (1)Osteonecrosis (1)Infections (2) Fractures (2)Hyperglycemia (1)Extravasation (1)	Myocardial infarction (1)Pulmonary embolism (1)Pneumonia (1)Seizure (1) Pancreatitis (1) Fever (1) Suicide attempt (1)Fractures (2) Wound (1) Surgery (1)Miscellaneous (2)

CPM = Cyclophosphamide; MP = Methylprednisolone;