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. 2004 Sep 15;5(1):12. doi: 10.1186/1465-9921-5-12

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Copyright © 2004 Koth et al; licensee BioMed Central Ltd.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Aspergillus antigen induced similar lung fibrosis in wild-type, Mcp-1^-/-and Ccr2^-/-mice. Left lungs from Aspergillus antigen- or PBS-treated wild-type, Mcp-1^-/-and Ccr2^-/-mice were analyzed for total hydroxyproline content as described in methods. Results are expressed as mean ± SE (N = 10 mice/group). Aspergillus antigen exposure and sample collection are described in methods; data are representative of two separate experiments. Asterisks (*) indicate values that are statistically significantly different (p < 0.001) compared to PBS controls.