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. 2004 Sep 15;5(1):12. doi: 10.1186/1465-9921-5-12

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Copyright © 2004 Koth et al; licensee BioMed Central Ltd.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Increased airway subepithelial collagen deposition after treatment with Aspergillus antigen. Representative lung sections from PBS-treated mice show minimal trichrome staining around small airways (A) (similar findings from Mcp-1^-/-and Ccr2^-/-control mice are not shown). Increased trichrome staining is noted around small airways in Aspergillus antigen-treated wild-type (B), Mcp-1^-/-(C) and Ccr2^-/-(D) mice. Blue staining around airways represents collagen. Aspergillus antigen exposure and sample collection are described in methods. Magnification, 20× objective.