|
Study
|
Age,
Gender, Race
|
Clinical Symptoms
|
Laboratory
|
CNS Imaging (modality)
|
Biopsy Source
|
Other Organ Involvement
|
Treatment, Response
|
|
Van der Vliet et al., 2004 [10]
|
66, F, not reported
|
Nausea, headache, swollen salivary gland
|
Hypothyroidism, increased serum IgG4
|
Sellar mass (CT)
|
Submandibular mass
|
Present
|
Prednisone, marked
|
|
Yamamoto et al., 2006 [11]
|
70, M, Japanese
|
Swollen salivary glands, sexual dysfunction
|
Hypogonadism, increased IgG4
|
Enlarged pituitary stalk (MRI)
|
Submandibular mass
|
Present
|
Prednisolone; marked
|
|
Tanabe et al., 2006 [12]
|
71, M, Japanese
|
Fatigue, weight loss, polydipsia, swollen salivary glands
|
Panhypopituitarism, increased IgG4
|
Swelling of pituitary (MRI)
|
Salivary gland and retroperitoneal mass
|
Present
|
Hydrocortisone, marked
|
|
Ralli et al., 2007 [13]
|
67, M, not reported
|
Generalized weakness
|
Panhypopituitarism, increased IgG4
|
Enlarged stalk and pituitary (MRI)
|
Pancreas
|
Present
|
Prednisone, marked
|
|
Wong et al., 2007 [14]
|
77, M, Chinese
|
Blurred vision
|
Hypogonadism, increased IgG4
|
Pituitary mass (MRI)
|
Pituitary, pancreas, gallbladder
|
Present
|
Hydrocortisone, not known
|
|
Isaka et al., 2008 [15]
|
55, M, Japanese
|
Fatigue, polyuria/polydipsia, nasal discharge
|
Diabetes insipidus (DI)
|
Enlarged stalk (MRI); Mass in sphenoidal, maxillary, frontal sinuses (CT)
|
Paranasal mass
|
Present
|
Prednisone, marked
|
|
Tsuboi et al., 2008 [16]
|
62, M, Japanese
|
Fatigue, weight loss, fever
|
Hypocortisolism, hypothyroidism, DI
|
Enlarged stalk (MRI);
|
Lung
|
Present
|
Glucocorticoid, good
|
|
Osawa et al., 2009 [17]
|
74, F, Japanese
|
Fatigue, polydipsia
|
Panhypopituitarism
|
Swelling of pituitary (MRI)
|
Pituitary
|
None
|
Glucocorticoids; marked
|
|
Hori et al., 2010 [18]
|
70, M, Japanese
|
Fatigue, thirst, nausea
|
DI, adrenal insufficiency, increased IgG4
|
Enlarged pituitary and stalk (MRI)
|
Salivary gland, liver, lung
|
Present
|
Hydrocortisone, marked
|
|
Haraguchi et al., 2010, case 1 [19]
|
74, F, Japanese
|
Fatigue, anorexia, polyuria, polydipsia
|
Panhypopituitarism, DI, increased IgG4
|
Swelling of pituitary and stalk (MRI)
|
None
|
None
|
Prednisone, marked
|
|
Haraguchi et al., 2010, case 2 [19]
|
68, M, Japanese
|
Polyuria, polydipsia
|
DI
|
Enlargement of stalk (MRI)
|
Retroperitoneal
|
Present
|
Prednisolone, good
|
|
Leporati et al., 2011 [8]
|
75, M, Caucasian
|
Headache
|
Panhypopituitarism
|
Enlarged pituitary, sphenoid sinus mass (MRI)
|
Pituitary
|
Present
|
Prednisolone, good
|
|
Patel et al., 2011 [20]
|
55, M, Native American
|
Weight loss, fever, headache, fatigue, polyuria, diplopia
|
Panhypopituitarism, increased IgG4
|
Enlarged pituitary (MRI)
|
Kidney, retroperitoneal, lymph nodes, lacrimal gland
|
Present
|
Prednisone, marked
|
|
Hsing et al., 2013 [21]
|
66, M, Chinese
|
Weight loss, nausea, vomiting
|
Hypogonadism, hypoadrenalism
|
Sellar mass (MRI)
|
Posterior mediastinal mass, pituitary mass
|
Present
|
Prednisolone, good
|
|
Hattori et al., 2013 [22]
|
55, M, Japanese
|
Bitemporal hemianopsia
|
Increased IgG4
|
Enlarged pituitary gland (unknown)
|
Pituitary
|
None
|
Prednisolone, good
|
|
Caputo et al., 2014 [23]
|
40, M, Vietnamese
|
Lethargy, polyuria, polydipsia
|
Panhypopituitarism, DI
|
Pituitary lesion (MRI)
|
Lacrimal gland, pituitary
|
Present
|
Prednisolone, incomplete; azathioprine, good
|
|
Kanoke et al., 2013, case 1 [24]
|
53, F, not reported
|
Headache
|
Hyperprolactinemia
|
Pituitary mass (MRI)
|
Pituitary with dura
|
Present
|
Hydrocortsone, good
|
|
Kanoke et al., 2013, case 2 [24]
|
27, F, not reported
|
Hx of germinoma, headache and fatiguability
|
Panhypopituitarism and hypothyroidism
|
Sellar lesion (MRI)
|
Pituitary with dura
|
None
|
Hydrocortisone, unknown
|
|
Present case
|
16, F, unknown
|
Polyuria, polydipsia
|
DI
|
Sellar mass (MRI)
|
Pituitary
|
None
|
Hydrocortisone unknown
|
