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Inhibition kinetics for dehydrogenase in vitro activity as a function of ADP and ATP. (A) GAPDH; (B) LDH; (C) ADH. The inhibitors were ATP (○) and ADP (•). ADPcrit and ATPcrit are the inhibitor concentrations at which the enzyme was totally inhibited, and n is the degree of inhibition. The values for these parameters were estimated by fitting equation 2 through the data points.
