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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Neurobiol Aging. 2016 Nov 21;50:134–143. doi: 10.1016/j.neurobiolaging.2016.11.006

Fig 1. Behaviors unaltered by forebrain deletion of Rheb.

Fig 1

(A) Research Scheme. (B) Average body weight of Rhebf/f& Rhebf/+ (Con), cRhebf/+;CamKIICre (Rheb-Het), cRhebf/f;CamKIICre (Rheb-Null) mice. (C–E) Analysis of open field exploration behavior for (C) average velocity, (D) distance traveled, or (E) duration spent in the center of the field. (F–H) Analysis of elevated plus maze exploration behavior for (F) percentage (%) of entries in open arms, (G) percentage of time spent in open arms, and (H) number of entries in all arms of the maze. (I–J) Analysis of contextual fear conditioning for (I) percentage of time freezing during training, and (J) percentage of time freezing during context testing (24 h or 15 days post-training). All values are mean ± SEM. Rhebf/f& Rhebf/+ (Con), n=21; cRhebf/+/CamKIICre (Rheb-Het), n=13; cRhebf/f;CamKIICre (Rheb-Null), n=18, one-way ANOVA followed by Tukey’s post hoc test was used There were no significant differences in any of these behaviors between the three groups. n.s.: not significant