Skip to main content
. Author manuscript; available in PMC: 2018 Jan 15.
Published in final edited form as: Toxicol Lett. 2016 Dec 8;266:23–31. doi: 10.1016/j.toxlet.2016.12.007

Figure1. Steps of natural killer (NK) cell-mediated cytotoxicity.

Figure1

NK cells survey and are educated by their surrounding cells (surveillance and licensing), and conjugate with cells devoid of MHC I (conjugation). The lytic granules in NK cells are polarized (granule polarization) and released (degranulation). Tumor cells undergo apoptosis subsequently (cytotoxicity).