Fig. 7.

Plots showing our reference calculations compared to experiment. Shown here is the results for submission 39 in SAMPL5, with no tautomer correction (log P), distribution coefficient corrected from calculated partition coefficient based on pKas ( $\log D_{{\mathit{pK}}_{\mathrm{a}}}$), and distribution coefficient corrected from calculated partition coefficient based on state penalties (log D_{state penalty}).