Table 2.

Predictive value for 90-day mortality with Wald statistics of lactate and bio-ADM at each time point after the detection of shock

	x 2	P value
0 h
Lactate	38.44	<0.0001
Bio-ADM	0.09	0.8
Total	42.76	<0.0001
12 h
Lactate	23.99	<0.0001
Bio-ADM	4.28	0.039
Total	46.69	<0.0001
24 h
Lactate	38.03	<0.0001
Bio-ADM	2.41	0.12
Total	44.82	<0.0001
48 h
Lactate	3.14	0.077
Bio-ADM	9.79	0.002
Total	20.58	<0.0001
72 h
Lactate	2.52	0.11
Bio-ADM	8.01	0.0047
Total	15.08	0.0005
96 h
Lactate	0.18	0.7
Bio-ADM	17.01	<0.0001
Total	19.95	<0.0001

Lactate and bio-ADM levels were log10-transformed for the analysis. During the first 24 h, only lactate contributes to mortality prediction, later only bio-ADM contributes to prediction