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. 2016 Jul 11;19(1):68–76. doi: 10.1007/s11307-016-0979-0

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© The Author(s) 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — Study design. a Three experimental groups were injected with [¹¹C]PBR28, subjected to PET imaging of the abdomen and sacrificed for ex vivo biodistribution to determine standardized uptake values (SUV) in various organs and tissues. The healthy control group (n = 6, white) was terminated at day 4. 2,4,6-Trinitrobenzenesulfonic acid (TNBS) [30 mg/rat]-treated rats were terminated at either at day 4 (n = 6, gray) or day 11 (n = 6, black). b A group of rats (n = 6) was investigated by PET imaging of the brain 14 days before TNBS injection (baseline) and 4 and 11 days after TNBS injection.