Table 4.
Inpatient costs of treating grade 3 or 4 events due to treatment for metastatic melanoma
| Adverse event | Italy | Spain | Germany | France | Netherlands | UK | Australia | Canada |
|---|---|---|---|---|---|---|---|---|
| Anemia | €2667 | €1801 | €2367 | €2000 | €2839 | £2246 | $4380 | $5181 |
| Cutaneous squamous cell carcinoma | €1589 | €1221 | €1544 | €1416 | €2122 | £1692 | $2379 | $8934 |
| Diarrhea | €1456 | €4113 | €1348 | €1585 | €1456 | £4284 | $4572 | $4320 |
| Diarrhea (immune related) | €1456 | €4113 | €1348 | €1585 | €1456 | £4284 | $4572 | $4320 |
| Dyspnea | €1689 | €1755 | €9077 | €1466 | €1431 | £1209 | $3671 | $5506 |
| Elevated liver enzymes | €2159 | €3356 | €1809 | €6913 | €1305 | £1819 | $6594 | $8030 |
| Febrile neutropenia | €2357 | €5480 | €2388 | €2000 | €2152 | £4444 | $5224 | $7843 |
| Fever | €3433 | €2822 | €1686 | €1658 | €1411 | £1598 | $4375 | $5008 |
| Headache | €2366 | €2489 | €1644 | €1002 | €1718 | £1372 | $1935 | $3479 |
| Hypertension | €1573 | €2405 | €2246 | €1619 | €1702 | £3852 | $4711 | $7028 |
| Hypophysitis | €1589 | €10,265 | €1979 | €5316 | €1683 | £2417 | $7231 | $9735 |
| Infection | €3433 | €4477 | €2099 | €3018 | €1806 | £1918 | $7199 | $6563 |
| Neutropenia | €2357 | €1529 | €2388 | €2000 | €877 | £2194 | $5224 | $7843 |
| Palmar plantar hyperkeratosis | €1308 | €5121 | €1544 | – | €1606 | £1692 | $2654 | $4177 |
| Peripheral neuropathy | €1972 | €4144 | €2004 | €2625 | €6977 | £2617 | $4923 | $9472 |
| Rash | €1308 | €2087 | €1544 | – | €1764 | £1692 | $2654 | $3223 |
| Vomiting | €1456 | €1755 | €1348 | €1585 | €2045 | £1702 | $4572 | $3543 |