Fig. 3.

Anastomotic ileal recurrent Crohn’s disease with high skewness on MRTA and increased histological inflammation (AIS score of 7). a Axial T2-weighted coronal SSTSE through the neoterminal ileum (arrow) attracting a Crohn’s disease activity score of 9 (large ROI) and skewness of 0.5346 (small ROI). b Coronal section of the bowel through the resection specimen matched to the site of sampling on MRI. c Full thickness H&E stained histological section (×12.5 magnification) showing mucosal ulceration and transmural inflammation with lymphoid aggregates. d H&E-stained histological section, ×100 magnification) shows confluent mucosal ulceration. e H&E-stained histological section (×200 magnification) taken from the region of the star in D shows an acute inflammatory cell infiltrate extending into the muscularis propria