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. 2016 Dec 15;8(12):5286–5297.

Figure 7.

Figure 7

The role of LINC00152 and miR-367c-3p in CRC. A. LINC00152 down-regulated by miR-367c-3p decreases the expression of proliferation-related molecule Ki-67 and anti-apoptosis molecule Bcl-2, and increases the expression of pro-apoptosis molecule Bax in CRC cells, further suppressing viability and promoting apoptosis in CRC cells. B. The abnormally low level of LINC00152, possibly induced by the aberrant up-regulation of miR-367c-3p, will lead to an increase of CRC cell growth, and may be involved in the tumorigenesis and progression of CRC.