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miR-214 inhibitor injection improved AVC in hypercholesterolemic apoE-/- mice. A: Percentage of AVC in apoE-/- mice fed a HC diet relative to that of the NC injection apoE-/- mice and miR-214 inhibitor injection apoE-/- mice fed a normal diet. B: TWIST1 mRNA and protein expression levels in the aortic valves of apoE-/- mice. **P < 0.01 compared with normal diet, ##P < 0.01 compared with HC diet +NC.
