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Corticospinal neuron (SPI) models replicate in vitro subthreshold responses to current injections, including bidirectional Ih-dependent sag in somatic membrane potential. The 1-s subthreshold somatic current injection starts at 500 ms (−0.1, −0.05, 0.05, and 0.1-nA current injections arrayed from bottom to top). Black: experiment; red: detailed SPI neuron model; blue: simplified SPI neuron model.
