Table 2.
Results of Gene Ontology functional and pathways enrichment analyses for genes positively regulated by differentially time-series expressed lncRNAs.
| Category | Term | Adjust p value | Gene count | Genes |
|---|---|---|---|---|
| GO-BP | Vasculature development [GO:0001944] | 1.33E − 08 | 65 | Adamts1, Cdh5, Ctsh, Cxcr3, Dhcr7, Edn1, Efna1, Efnb2, Notch3, Pdgfrb, and so on |
| GO-BP | Blood vessel development [GO:0001568] | 1.34E − 07 | 60 | Adamts1, Cdh5, Ctsh, Cxcr3, Dhcr7, Edn1, Efna1, Efnb2, Notch3, Pdgfrb, and so on |
| GO-BP | Regulation of locomotion [GO:0040012] | 2.45E − 05 | 51 | Dab2, Ifitm3, Il16, Il33, Irs2, Megf8, Myo1f, Pdgfrb, Pecam1, Pkn1, and so on |
| GO-BP | Blood vessel morphogenesis [GO:0048514] | 2.55E − 05 | 49 | Adamts1, Aqp1, C3, Ccr2, Edn1, Efna1, Efnb2, Egfl7, Elk3, Ephb4, and so on |
| GO-BP | Regulation of cellular component movement [GO:0051270] | 3.92E − 05 | 50 | Ccl21a, Dab2, Ddr2, Dpep1, Efna1, Nup155, Pde4d, Pdgfra, Pdgfrb, Pecam1, and so on |
| GO-CC | Cell surface [GO:0009986] | 2.46E − 05 | 53 | Ackr3, Alcam, Cd200r1, Cd3e, Dpp4, Enpp1, Flt3l, Heg1, Ifitm3, Il2rb, and so on |
| GO-CC | Plasma membrane [GO:0005886] | 9.39E − 05 | 158 | Ano1, Antxr1, Aqp1, Capn3, Ccr2, Itga5, Itm2c, Kcnab1, Kcnn3, Kcnt2, and so on |
| GO-CC | Cell periphery [GO:0071944] | 2.59E − 04 | 163 | Antxr1, Aqp1, Bcas3, Capn3, Eps15l1, Ezr, Krt19, Lime1, Ntn4, P2rx4, and so on |
| GO-CC | Side of membrane [GO:0098552] | 0.015056 | 33 | Alcam, Ano1, Cd74, Ikbkb, Il2rb, Itga5, Kdr, Ly6a, Ly6c1, Pkp4, and so on |
| GO-CC | Plasma membrane part [GO:0044459] | 0.021127 | 101 | Klri1, Lime1, Ly6a, Npc1, P2rx4, Sema6a, Sept2, Tspan15, Upk1b, Zdhhc2, and so on |
| REACT_208531 | Cholesterol biosynthesis | 4.00E − 03 | 9 | Cyp51, Dhcr7, Fdps, Hsd17b7, Idi1, Lss, Mvk, Sc5d, Sqle |
| REACT_198996 | Elastic fibre formation | 5.10E − 03 | 11 | Efemp1, Efemp2, Fbln1, Fbln2, Fbln5, Furin, Itga5, Loxl1, Ltbp1, Mfap3, and so on |
The GO-BP terms in the table are the top 5 ones with a higher adjusted p value. DE-lncRNA, differentially time-series expressed long noncoding RNA gene; GO, Gene Ontology; BP, biological process; CC, cellular component. “REACT” terms are the pathway terms.