Table 2.
Patient demographics and blood analysis before treatment among groups 1, 2, 3, and 4.
| Variables | Group 1 | Group 2 | Group 3 | Group 4 | F/χ2 value | P |
|---|---|---|---|---|---|---|
| Cases | 40 | 52 | 21 | 19 | — | — |
| Age (year) | 54.32 ± 10.14 | 58.31 ± 9.24 | 59.10 ± 7.55 | 60.37 ± 8.05 | 2.587 | 0.056 |
| Sex (M/F) | 24/16 | 31/21 | 12/9 | 11/8 | 0.064 | 0.996 |
| Educational years | 9.55 ± 3.37 | 10.37 ± 3.33 | 9.19 ± 2.87 | 8.63 ± 2.75 | 1.662 | 0.178 |
| Etiology | 7.148 | 0.711 | ||||
| B viral hepatitis cirrhosis | — | 21 | 11 | 8 | ||
| C viral hepatitis cirrhosis | — | 1 | 1 | 1 | ||
| Primary biliary cirrhosis | — | 3 | 3 | 1 | ||
| Autoimmune hepatitis cirrhosis | — | 5 | 0 | 3 | ||
| Schistosomiasis cirrhosis | — | 6 | 1 | 1 | ||
| Cryptogenic cirrhosis | — | 16 | 5 | 5 | ||
| Child-Pugh grading | 7.229 | 0.124 | ||||
| Grade A | — | 18 | 4 | 2 | ||
| Grade B | — | 21 | 8 | 7 | ||
| Grade C | — | 13 | 9 | 10 | ||
| Child-Pugh scores | — | 8.27 ± 2.36 | 9.19 ± 2.16 | 10.16 ± 2.27 | 4.965 | 0.009 |
| Ammonia (μmol/L) | — | 37.12 ± 15.28 | 63.81 ± 19.22 | 106.21 ± 46.14 | 52.154 | <0.001 |
| Cr (μmol/L) | — | 86.01 ± 22.80 | 83.35 ± 40.11 | 79.14 ± 43.92 | 0.318 | 0.728 |
| TBil (μmol/L) | — | 45.78 ± 16.76 | 45.57 ± 14.51 | 42.81 ± 14.83 | 0.254 | 0.776 |
| ALB (g/L) | — | 29.62 ± 7.92 | 28.38 ± 5.36 | 31.05 ± 6.71 | 0.691 | 0.504 |
| PT (sec) | — | 3.14 ± 1.76 | 2.87 ± 1.74 | 3.25 ± 1.76 | 0.263 | 0.769 |
| NCT-A (sec) | 46.92 ± 11.80 | 51.31 ± 10.93 | 88.29 ± 9.38 | — | 108.840 | <0.001 |
| DST (scores) | 52.35 ± 10.69 | 49.98 ± 9.98 | 23.57 ± 4.04 | — | 72.476 | <0.001 |
Table 2 indicates comparison of age, sex, educational years, etiology, Child-Pugh grading, Child-Pugh scores, ammonia, Cr, TBil, ALB, PT, NCT-A, and DST among groups 1, 2, 3, and 4 before treatment. Group 1 is healthy controls group, group 2 is cirrhosis without HE group, group 3 is cirrhosis with MHE group, and group 4 is cirrhosis with OHE group. Continuous data were compared using ANOVA and categorical data were compared by a chi-square test. P < 0.05 means significant differences in an index among groups.