Table 1.

Results of linear regression analyses of the continuous genetic risk score against the continuous age at menarche variable and confounders

		Genetic risk score
Variable	n	Estimate (95% CI)	P
Age at menarche (months)	2772	−0.42 (−0.49 to −0.35)	1.410−28
Body mass index at age 9	2705	0.04 (0.02 to 0.05)	2.010−5
Body mass index at age 15	2122	0.05 (0.03 to 0.07)	2.010−5
Maternal antenatal depression	2590	0.01 (−0.01 to 0.02)	0.34
Maternal postnatal depression	2684	−0.002 (−0.02 to 0.01)	0.80
Maternal age	2709	−0.02 (−0.06 to 0.02)	0.30
Maternal education	2745	−0.001 (−0.01 to 0.00)	0.81
Social class	2645	1.010−14 (−0.01 to 0.01)	0.98
Financial problems	2704	−0.003 (−0.01 to 0.00)	0.20
Home ownership	2922	−0.004 (−0.02 to 0.01)	0.56
Father absence	2747	0.002 (0.00 to 0.01)	0.15
Siblings, n	2741	1.010−14 (0.00 to 0.00)	0.85