FIGURE 5.
Tissue biodistribution of 3H-2-F-PABA and 3H-2-F-mannitol in murine myositis model. Mice were inoculated with live bacteria in right thigh and 10-fold-higher burden of heat-killed bacteria in left thigh (sterile inflammation). Tracer was injected intravenously and accumulation in tissues measured using scintillation counting from surgically resected tissues. Tissue biodistribution of 3H-2-F-PABA (A) (n = 4 animals) and 3H-2-F-mannitol (B) (n = 4 animals) is shown. *P = 0.03 (Mann–Whitney U test, 2-tail). Median, interquartile, and range are shown.