Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jan 4;7:39721. doi: 10.1038/srep39721

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Kaplan-Meier curves for the OS of metastatic lung adenocarcinoma patients according to KRAS mutation status in patients with (A) lung, (B) bone, (C) adrenal, (D) brain, (E) pleura, and (F) liver spread. Both single- and multiple-organ metastatic cases were included in these analyses. We found a clinically relevant and also significant decrease in OS in patients presented with KRAS mutant bone metastasis (vs KRAS wild-type, median OS 3.7 v 9.7 months; HR, 0.49; 95% CI, 0.31 to 0.79; p = 0.003). Importantly, we found no statistically significant information in any other organ-specific comparison.