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. 2017 Jan 3;18:10. doi: 10.1186/s12859-016-1422-x

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© The Author(s) 2017

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Predictions based on highly interacting modules. a, b Flagella signaling example. Predictions based on highly interacting modules. Module 30 consist of four chemotaxis signaling complexes: ribose/galactose/glucose sensing, dipeptide sensing, serine sensing, aspartate sensing. CheY, CheZ, CheR, CheB also interacts with either these complexes or CheA which is in the core of these complexes. c Pilus assembly example. In Module 324: FimC, FimD, FimG, and FimH are part of recently characterized Pilus assembly complex [30]