Table 1.
Co-expression module characteristics
| Module | No. of genes | Variance explained by eigengene | Top ten hub genes (kME>0.9) |
|---|---|---|---|
| M1 | 740 | 44.6% | ZNF845, ZNF808, GPR160, GIN1, ATP5J, ZNF567, ANAPC10, C8orf59, MRPS36, RBM7 |
| M2 | 262 | 48.9% | EPHA10, ARIH2OS, TUBD1, FLJ42102, KIAA0101, RPL13AP20, CD96, PDE6A, GGT8P, SLC35F1 |
| M3 | 844 | 79.6% | NOTCH3, PLXND1, PALM, CSPG4, ARHGEF17, DCHS1, MARK4, KIRREL, LTBP4, AXL |
| M4 | 566 | 51.5% | HMMR, CASC5, DEPDC1, CDK1, KIF15, CCNA2, AIM1, TTK, ESCO2, EXO1 |
| M5 | 116 | 45.5% | ATP2A1, C11orf35, P2RY2, CCDC33, ASIC3, KIFC2, IL17REL, CLIC3, MTVR2, RBBP8NL |
| M6 | 88 | 51.4% | HN1, ASAP3, SLC12A8, ASPHD2, B3GNT7, IL17RE, PRG2, NOG, IL2RB, PIPOX |
| M7 | 112 | 41.5% | SNORD114-29, CDH11, FAM198B, SNORD114-7, SNORD114-10, FKBP7, SNORD114-14, C4orf32, SNORD114-26, SNORD113-2 |
| M8 | 390 | 68.1% | SBF1, ULK1, STRA6, DOT1L, BCAR1, TMEM184A, B3GNT8, SLC25A22, C19orf71, INTS1 |
| M9 | 79 | 44.5% | SELL, S100A12, LRRK2, CYTIP, MNDA, ACSL1, FPR2, TGFA, LOC100505806, TMEM71 |
| M10 | 110 | 39.1% | MTHFS, TTTY15, RPS4Y1, TXLNG2P, TTTY10, KDM5D, UTY, EIF1AY, ZFY, PRKY |
| M11 | 112 | 43.1% | PGAP3, GPR137, PRR5, ARTN, C10orf10, C7orf43, ALDH4A1, EFS, RELL2, ADIRF |
| M12 | 81 | 51.7% | PVRL4, ARHGEF4, NDRG1, INHBA, SYDE1, INHA, MIR210HG, C8orf58, SIGLEC6, PDZD7 |
| M13 | 414 | 71.0% | FAM195B, FBXL15, BRAT1, AKAP2, SCAND1, EME2, CCDC85B, C19orf60, PGLS, TSR3 |