Table 1.
Cell surface determinant expression by human lung and skin MPCs
| MPC | Age, years | Sex | CD44 | CD73 | CD105 | CD106 | CD146 | CD140b | CD14 | CD31 | CD34 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human lung MPCs | |||||||||||
| Control 1 | 57 | M | 99.0 | 99.4 | 98.6 | 6.5 | 53.2 | 90.4 | 0 | 0.1 | 0 |
| Control 2 | Unknown | M | 99.8 | 100 | 99.9 | 0.44 | 33.1 | 99.9 | 0 | 0 | 0 |
| Control 3 | 66 | F | 98.9 | 99.9 | 99.9 | 0.46 | 31.3 | 99.5 | 0 | 0 | 0 |
| Control 4 | 35 | M | 100 | 100 | 100 | 3.73 | 5.31 | 95 | 0 | 0 | 0 |
| HPAH | 12 | F | 100 | 100 | 100 | 7.64 | 63.1 | 90.2 | 0 | 0 | 0 |
| IPAH 1 | 32 | F | 99.1 | 99.7 | 83.6 | 0.72 | 53.8 | 97 | 0 | 0.025 | 0.024 |
| IPAH 2 | Unknown | F | 99.9 | 99.6 | 96.9 | 9.74 | 72.3 | 93.2 | 0.015 | 0 | 0.015 |
| Human skin MPCs | |||||||||||
| Control 1 | 45 | F | 99.9 | 100 | 100 | 0.19 | 46.9 | 98.7 | 0 | 0 | 0.4 |
| Control 2 | 40 | F | 99.9 | 95.4 | 100 | 0.13 | 48.5 | 99.9 | 0.1 | 0 | 0.1 |
Note
Unless otherwise specified, data are percentages. HPAH: heritable pulmonary arterial hypertension; IPAH: idiopathic pulmonary arterial hypertension; MPC: mesenchymal progenitor cell.