Table S1.
Raw data of pixel density for cytokines included in Proteome Profiler Human XL Cytokine antibody array kit (R&D Systems, Minneapolis, MN) performed at R&D Systems in duplicate for controls (n = 3) and patients with portopulmonary hypertension (POPH; n = 3)
| Control | POPH | |||||
|---|---|---|---|---|---|---|
| Biomarker | 1 | 2 | 3 | 1 | 2 | 3 |
| Adiponectin (a) | 49,475.05 | 51,813.08 | 53,522.44 | 55,451.35 | 57,121.03 | 51,293.78 |
| Adiponectin (b) | 48,409.73 | 49,735.91 | 53,539.46 | 53,638.29 | 56,941.99 | 53,726.59 |
| Aggrecan (a) | 42,337.03 | 33,407 | 39,124.06 | 37,635.05 | 43,924.06 | 43,649.43 |
| Aggrecan (b) | 43,803.35 | 34,796.37 | 39,260.97 | 37,627.76 | 44,340.47 | 44,042.34 |
| Angiogenin (a) | 48,575.81 | 47,943.91 | 51,092.87 | 50,782.59 | 53,224.32 | 54,202.95 |
| Angiogenin (b) | 47,950.39 | 49,051.35 | 48,820.47 | 49,131.56 | 50,935.71 | 53,827.05 |
| Angiopoietin-1 (a) | 4,577.84 | 7,119.2 | 4,712.32 | 5,570.24 | 6,515.66 | 5,567.81 |
| Angiopoietin-1 (b) | 4,270.8 | 6,897.23 | 4,054.49 | 5,721.73 | 5,888.62 | 5,311.81 |
| Angiopoietin-2 (a) | 7,388.97 | 4,646.7 | 5,370.14 | 6,734.39 | 6,149.48 | 11,491.46 |
| Angiopoietin-2 (b) | 6,974.19 | 4,525.99 | 5,071.2 | 6,541.58 | 5,816.52 | 10,307.86 |
| BAFF (a) | 36,824.92 | 12,810.34 | 14,595.86 | 31,761.63 | 12,899.46 | 29,878.09 |
| BAFF (b) | 35,090.44 | 12,770.65 | 14,148.67 | 30,428.97 | 12,428.77 | 27,502.8 |
| BDNF (a) | 4,868.67 | 4,154.14 | 4,848.42 | 5,141.68 | 5,105.23 | 6,755.46 |
| BDNF (b) | 4,503.3 | 4,230.29 | 4,483.05 | 4,983.71 | 4,812.77 | 6,235.35 |
| C-reactive protein (a) | 54,720.62 | 57,038.39 | 55,866.95 | 47,585.03 | 61,840.01 | 56,670.59 |
| C-reactive protein (b) | 52,023.71 | 56,764.57 | 56,988.16 | 41,436.97 | 63,026.04 | 56,401.63 |
| C5/C5a (a) | 26,880.62 | 26,495.81 | 28,324.27 | 22,486.49 | 34,547.66 | 28,819.25 |
| C5/C5a (b) | 27,324.57 | 26,209.84 | 28,707.46 | 22,821.89 | 34,077.78 | 29,083.35 |
| CD14 (a) | 21,054.19 | 14,609.63 | 18,332.97 | 18,935.71 | 26,904.11 | 25,932.77 |
| CD14 (b) | 19,336.72 | 15,288.52 | 19,893.28 | 19,371.56 | 26,252.77 | 27,424.22 |
| CD30 (a) | 4,303.2 | 4,010.75 | 6,633.13 | 4,270.8 | 4,289.43 | 4,581.08 |
| CD30 (b) | 4,634.54 | 4,183.3 | 7,536.42 | 4,628.06 | 4,748.77 | 4,483.86 |
| CD40 ligand (a) | 6,127.61 | 4,913.23 | 7,488.62 | 7,002.54 | 7,017.13 | 7,020.37 |
| CD40 ligand (b) | 7,797.28 | 5,099.56 | 7,313.63 | 7,405.18 | 7,789.99 | 7,788.37 |
| Chitinase 3-like 1 (a) | 57,829.89 | 59,574.9 | 59,099.35 | 56,523.96 | 60,417.43 | 57,890.65 |
| Chitinase 3-like 1 (b) | 58,441.53 | 59,017.53 | 56,608.22 | 55,395.46 | 58,857.13 | 58,610.04 |
| Complement factor D (a) | 45,576.72 | 45,046.09 | 46,562.65 | 45,570.24 | 49,713.23 | 48,519.91 |
| Complement factor D (b) | 43,177.94 | 43,029.68 | 45,726.59 | 44,027.76 | 48,474.54 | 48,539.35 |
| Cripto-1 (a) | 4,456.32 | 4,342.9 | 5,769.53 | 5,609.13 | 5,932.37 | 4,816.01 |
| Cripto-1 (b) | 4,308.87 | 4,070.7 | 5,148.16 | 5,344.22 | 5,042.04 | 4,285.38 |
| Cystatin C (a) | 42,534.7 | 38,213.48 | 40,565.28 | 37,703.1 | 41,587.66 | 47,457.03 |
| Cystatin C (b) | 42,581.68 | 39,012.27 | 40,379.76 | 37,946.95 | 42,130.44 | 46,264.52 |
| Dkk-1 (a) | 4,610.24 | 4,376.92 | 4,345.33 | 4,321.84 | 4,434.44 | 4,572.16 |
| Dkk-1 (b) | 4,322.65 | 4,222.19 | 4,004.27 | 4,322.65 | 4,123.35 | 4,406.9 |
| DPPIV (a) | 19,430.7 | 14,381.18 | 24,554.75 | 11,702.9 | 35,501.18 | 38,807.3 |
| DPPIV (b) | 19,316.47 | 14,224.82 | 23,883.96 | 11,749.89 | 35,797.68 | 39,267.46 |
| EGF (a) | 5,270.49 | 4,368.82 | 4,946.44 | 5,410.65 | 6,691.46 | 5,624.52 |
| EGF (b) | 4,930.24 | 4,103.1 | 4,515.46 | 5,453.58 | 6,423.3 | 5,690.14 |
| Emmprin (a) | 25,514.75 | 17,168.01 | 24,142.39 | 21,741.18 | 29,767.91 | 32,976.01 |
| Emmprin (b) | 26,339.46 | 17,531.76 | 24,390.29 | 21,983.41 | 31,657.13 | 32,724.06 |
| ENA-78/CXCL5 (a) | 5,102.8 | 4,091.76 | 4,436.06 | 5,670.7 | 5,567 | 5,251.86 |
| ENA-78/CXCL5 (b) | 5,165.18 | 4,103.1 | 4,530.04 | 6,239.41 | 5,370.14 | 5,690.14 |
| Endoglin (a) | 42,504.72 | 39,474.04 | 40,132.67 | 40,569.33 | 45,897.53 | 44,485.48 |
| Endoglin (b) | 44,210.85 | 40,539.35 | 40,144.82 | 41,313.84 | 44,061.78 | 45,533.78 |
| Fas ligand (a) | 8,272.82 | 8,490.75 | 6,702.8 | 7,451.35 | 7,640.11 | 9,931.15 |
| Fas ligand (b) | 6,987.15 | 7,363.86 | 5,654.49 | 6,684.97 | 6,038.49 | 7,862.9 |
| FGF basic (a) | 7,225.33 | 6,184.32 | 5,836.77 | 10,375.1 | 7,203.46 | 7,942.29 |
| FGF basic (b) | 8,634.95 | 7,249.63 | 8,084.87 | 10,597.89 | 8,258.24 | 9,260.37 |
| FGF-19 (a) | 9,596.57 | 6,616.92 | 7,992.52 | 9,123.46 | 10,684.57 | 14,792.72 |
| FGF-19 (b) | 9,436.97 | 6,801.63 | 8,316.57 | 9,861.48 | 10,581.68 | 17,103.2 |
| FGF-7 (a) | 5,376.62 | 4,853.28 | 5,535.41 | 4,922.14 | 6,125.99 | 5,657.73 |
| FGF-7 (b) | 4,381.78 | 3,890.04 | 4,160.62 | 4,368.01 | 4,909.18 | 4,123.35 |
| Flt-3 ligand (a) | 5,109.28 | 3,975.1 | 6,268.57 | 6,198.09 | 5,014.49 | 9,035.96 |
| Flt-3 ligand (b) | 4,754.44 | 4,058.54 | 5,848.11 | 5,780.06 | 5,106.85 | 8,103.51 |
| G-CSF (a) | 3,949.99 | 3,894.09 | 3,909.48 | 4,120.11 | 4,139.56 | 4,252.97 |
| G-CSF (b) | 3,949.18 | 3,941.89 | 3,938.65 | 4,036.67 | 4,004.27 | 4,570.54 |
| GDF-15 (a) | 40,438.09 | 20,039.91 | 29,624.52 | 31,984.42 | 27,638.09 | 39,824.01 |
| GDF-15 (b) | 40,287.41 | 20,970.75 | 29,311 | 34,463.41 | 27,331.05 | 40,420.27 |
| GM-CSF (a) | 5,122.24 | 4,570.54 | 6,665.53 | 9,153.43 | 6,621.78 | 5,607.51 |
| GM-CSF (b) | 5,494.9 | 4,820.06 | 6,822.7 | 9,681.63 | 6,907.76 | 5,792.22 |
| GRO alpha (a) | 4,065.03 | 3,673.73 | 4,045.58 | 4,060.16 | 4,146.04 | 4,265.94 |
| GRO alpha (b) | 3,981.58 | 3,882.75 | 4,074.75 | 4,783.61 | 4,103.91 | 4,368.82 |
| Growth hormone (a) | 23,878.29 | 3,857.63 | 5,267.25 | 39,828.06 | 4,882.44 | 28,370.44 |
| Growth hormone (b) | 23,081.94 | 3,859.25 | 4,863.81 | 39,254.49 | 4,692.87 | 28,107.15 |
| HGF (a) | 7,046.29 | 4,243.25 | 4,288.62 | 6,411.15 | 5,659.35 | 11,729.63 |
| HGF (b) | 7,796.47 | 4,201.13 | 4,855.71 | 7,336.32 | 6,422.49 | 12,474.95 |
| I-TAC (a) | 4,071.51 | 3,897.33 | 4,021.28 | 4,889.73 | 4,073.94 | 5,148.97 |
| I-TAC (b) | 4,522.75 | 4,417.43 | 4,267.56 | 5,093.08 | 3,928.92 | 5,351.51 |
| ICAM-1 (a) | 43,559.51 | 34,089.94 | 43,228.16 | 46,172.97 | 46,892.37 | 46,414.39 |
| ICAM-1 (b) | 42,049.43 | 34,022.7 | 42,674.04 | 45,490.04 | 47,115.96 | 47,282.04 |
| IFN-gamma (a) | 4,627.25 | 4,165.48 | 4,502.49 | 5,598.59 | 4,836.27 | 5,136.01 |
| IFN-gamma (b) | 4,730.95 | 4,048.01 | 4,551.1 | 5,623.71 | 4,893.78 | 5,567 |
| IGFBP-2 (a) | 37,399.3 | 31,482.14 | 34,622.19 | 36,414.19 | 37,768.72 | 40,511.81 |
| IGFBP-2 (b) | 37,499.76 | 32,535.3 | 33,633.84 | 36,483.86 | 37,968.82 | 38,718.19 |
| IGFBP-3 (a) | 35,184.42 | 31,469.99 | 30,911.81 | 29,920.22 | 31,862.09 | 38,716.57 |
| IGFBP-3 (b) | 34,237.38 | 31,311.2 | 30,785.43 | 30,343.91 | 32,413.78 | 39,155.66 |
| IL-1 alpha (a) | 4,764.16 | 4,152.52 | 4,513.03 | 6,364.97 | 4,868.67 | 6,346.34 |
| IL-1 alpha (b) | 4,628.06 | 4,023.71 | 4,467.66 | 6,127.61 | 4,598.9 | 6,053.89 |
| IL-1 beta (a) | 4,323.46 | 3,676.16 | 3,916.77 | 4,762.54 | 4,828.97 | 4,760.92 |
| IL-1 beta (b) | 4,369.63 | 3,816.32 | 4,036.67 | 4,402.04 | 4,634.54 | 4,336.42 |
| IL-10 (a) | 4,343.71 | 3,909.48 | 4,073.94 | 4,389.08 | 5,101.18 | 4,396.37 |
| IL-10 (b) | 4,235.96 | 3,786.34 | 3,970.24 | 4,251.35 | 4,815.2 | 4,805.48 |
| IL-11 (a) | 5,751.71 | 4,666.95 | 5,916.16 | 6,945.84 | 5,901.58 | 7,281.23 |
| IL-11 (b) | 5,652.87 | 4,923.76 | 5,936.42 | 6,459.76 | 6,138.14 | 7,252.87 |
| IL-12 p70 (a) | 4,473.33 | 4,060.16 | 4,129.84 | 5,054.19 | 4,887.3 | 4,671 |
| IL-12 p70 (b) | 4,534.9 | 4,231.91 | 4,187.35 | 4,864.62 | 5,398.49 | 4,789.28 |
| IL-13 (a) | 4,346.95 | 4,049.63 | 4,267.56 | 4,628.06 | 4,769.03 | 4,897.84 |
| IL-13 (b) | 4,101.48 | 3,834.95 | 3,949.18 | 4,441.73 | 4,237.58 | 4,675.86 |
| IL-15 (a) | 4,354.24 | 3,614.59 | 4,058.54 | 4,779.56 | 4,631.3 | 4,649.94 |
| IL-15 (b) | 4,327.51 | 4,022.09 | 3,994.54 | 4,165.48 | 4,329.13 | 4,331.56 |
| IL-16 (a) | 3,926.49 | 4,112.01 | 3,903 | 4,240.01 | 3,998.59 | 4,269.99 |
| IL-16 (b) | 3,854.39 | 3,736.92 | 4,071.51 | 3,832.52 | 3,790.39 | 4,427.96 |
| IL-17A (a) | 8,203.96 | 6,341.48 | 10,859.56 | 10,640.82 | 11,412.87 | 23,004.97 |
| IL-17A (b) | 9,284.67 | 7,615.81 | 11,457.43 | 11,877.08 | 10,068.06 | 25,284.67 |
| IL-18 Bpa (a) | 13,595.35 | 10,921.13 | 15,762.44 | 13,524.06 | 14,612.06 | 19,831.71 |
| IL-18 Bpa (b) | 14,433.03 | 10,981.89 | 16,776.72 | 13,121.43 | 16,122.14 | 20,157.38 |
| IL-19 (a) | 4,373.68 | 4,036.67 | 4,388.27 | 5,250.24 | 4,639.41 | 5,689.33 |
| IL-19 (b) | 4,413.38 | 4,129.84 | 4,287.81 | 5,062.29 | 4,589.99 | 5,710.39 |
| IL-1ra (a) | 4,214.09 | 4,204.37 | 4,892.16 | 4,325.89 | 4,434.44 | 4,159 |
| IL-1ra (b) | 3,961.33 | 3,846.29 | 5,038.8 | 4,127.41 | 4,516.27 | 4,441.73 |
| IL-2 (a) | 4,366.39 | 3,735.3 | 4,251.35 | 4,924.57 | 4,981.28 | 4,516.27 |
| IL-2 (b) | 4,633.73 | 4,133.89 | 4,110.39 | 5,141.68 | 5,083.35 | 4,303.2 |
| IL-22 (a) | 4,445.78 | 3,935.41 | 4,407.71 | 4,851.66 | 5,264.01 | 5,724.97 |
| IL-22 (b) | 4,603.76 | 4,005.89 | 4,335.61 | 4,799 | 5,001.53 | 5,396.87 |
| IL-23 (a) | 3,846.29 | 3,558.7 | 3,796.87 | 3,971.05 | 3,941.08 | 4,162.24 |
| IL-23 (b) | 4,069.89 | 3,806.59 | 3,885.18 | 3,886.8 | 3,973.48 | 4,344.52 |
| IL-24 (a) | 4,102.29 | 4,088.52 | 3,947.56 | 4,117.68 | 4,048.82 | 4,259.46 |
| IL-24 (b) | 4,041.53 | 3,965.38 | 3,919.2 | 4,386.65 | 4,013.18 | 4,218.95 |
| IL-27 (a) | 4,251.35 | 4,025.33 | 4,457.13 | 4,581.08 | 4,557.58 | 5,665.84 |
| IL-27 (b) | 4,255.41 | 4,412.57 | 4,573.78 | 4,509.78 | 4,658.85 | 5,732.27 |
| IL-3 (a) | 4,086.9 | 3,843.86 | 3,959.71 | 4,289.43 | 4,500.87 | 4,009.13 |
| IL-3 (b) | 3,940.27 | 3,741.78 | 3,863.3 | 4,096.62 | 4,577.03 | 4,127.41 |
| IL-31 (a) | 3,528.72 | 3,979.96 | 3,889.23 | 4,052.87 | 4,081.23 | 3,950.8 |
| IL-31 (b) | 3,932.16 | 3,999.41 | 4,106.34 | 4,044.77 | 4,089.33 | 4,005.89 |
| IL-32 alpha/beta/gamma (a) | 4,115.25 | 3,886.8 | 4,007.51 | 4,043.15 | 4,014.8 | 4,300.77 |
| IL-32 alpha/beta/gamma (b) | 4,059.35 | 3,859.25 | 3,970.24 | 4,235.15 | 4,052.06 | 4,145.23 |
| IL-33 (a) | 3,706.95 | 4,003.46 | 4,244.87 | 3,941.89 | 3,911.91 | 4,107.15 |
| IL-33 (b) | 3,757.18 | 3,985.63 | 4,131.46 | 3,962.95 | 3,880.32 | 4,042.34 |
| IL-34 (a) | 4,701.78 | 3,842.24 | 4,161.43 | 4,688.82 | 4,532.47 | 4,154.95 |
| IL-34 (b) | 4,230.29 | 3,659.96 | 4,168.72 | 4,468.47 | 3,971.05 | 4,130.65 |
| IL-4 (a) | 4,349.38 | 3,886.8 | 4,282.95 | 4,479.81 | 4,827.35 | 5,532.16 |
| IL-4 (b) | 4,699.35 | 4,118.49 | 4,379.35 | 4,692.87 | 4,556.77 | 4,837.89 |
| IL-5 (a) | 3,546.54 | 3,724.77 | 3,986.44 | 4,411.76 | 3,938.65 | 3,920.82 |
| IL-5 (b) | 3,728.82 | 3,836.57 | 4,068.27 | 4,496.01 | 3,728.82 | 4,085.28 |
| IL-6 (a) | 4,662.09 | 4,062.59 | 4,993.43 | 6,101.68 | 5,687.71 | 7,356.57 |
| IL-6 (b) | 4,914.04 | 4,336.42 | 4,918.09 | 6,555.35 | 5,499.76 | 7,184.01 |
| IL-8 (a) | 4,903.51 | 4,905.94 | 4,929.43 | 5,752.52 | 8,023.3 | 5,511.1 |
| IL-8 (b) | 4,858.95 | 5,515.15 | 5,102.8 | 6,408.72 | 9,343.81 | 5,345.03 |
| IP-10 (a) | 4,361.53 | 4,318.59 | 4,184.92 | 4,305.63 | 4,607.81 | 4,610.24 |
| IP-10 (b) | 4,343.71 | 4,265.94 | 4,283.76 | 4,282.95 | 4,440.92 | 4,892.97 |
| Kallikrein 3 (a) | 4,473.33 | 4,349.38 | 4,574.59 | 5,565.38 | 4,556.77 | 7,008.22 |
| Kallikrein 3 (b) | 4,972.37 | 4,354.24 | 4,743.1 | 6,244.27 | 4,866.24 | 7,281.23 |
| Leptin (a) | 4,009.94 | 6,708.47 | 26,090.75 | 4,730.14 | 40,552.32 | 36,914.04 |
| Leptin (b) | 4,167.91 | 6,688.22 | 27,488.22 | 4,575.41 | 41,138.04 | 37,633.43 |
| LIF (a) | 4,118.49 | 3,816.32 | 4,092.57 | 3,856.01 | 4,039.91 | 3,962.14 |
| LIF (b) | 3,633.23 | 3,843.86 | 4,031 | 3,995.35 | 3,875.46 | 4,271.61 |
| Lipocalin-2 (a) | 43,935.41 | 41,867.96 | 39,126.49 | 41,435.35 | 41,511.51 | 44,251.35 |
| Lipocalin-2 (b) | 42,157.18 | 40,065.43 | 39,346.85 | 41,650.85 | 41,312.22 | 43,188.47 |
| M-CSF (a) | 5,320.72 | 4,393.94 | 4,261.89 | 6,151.91 | 4,873.53 | 6,012.57 |
| M-CSF (b) | 5,098.75 | 4,561.63 | 4,749.58 | 6,142.19 | 4,753.63 | 6,559.41 |
| MCP-1 (a) | 5,313.43 | 5,227.56 | 5,993.13 | 9,079.71 | 6,985.53 | 14,634.75 |
| MCP-1 (b) | 4,936.72 | 5,204.06 | 5,654.49 | 8,602.54 | 6,074.14 | 11,991.3 |
| MCP-3 (a) | 3,806.59 | 3,890.04 | 3,933.78 | 4,022.09 | 3,935.41 | 4,043.15 |
| MCP-3 (b) | 3,792.01 | 3,919.2 | 3,957.28 | 4,224.62 | 3,920.01 | 4,031.81 |
| MIF (a) | 9,643.56 | 12,099.05 | 8,366.8 | 15,056.82 | 16,461.58 | 17,806.39 |
| MIF (b) | 9,532.57 | 12,142.8 | 8,414.59 | 14,255.61 | 17,626.54 | 17,547.96 |
| MIG (a) | 3,928.92 | 4,771.46 | 5,245.38 | 4,417.43 | 4,513.03 | 4,763.35 |
| MIG (b) | 4,235.15 | 4,636.16 | 5,233.23 | 4,153.33 | 4,291.05 | 4,708.27 |
| MIP-1 alpha/MIP-1 beta (a) | 3,694.8 | 4,078.8 | 3,980.77 | 3,967.81 | 3,962.14 | 4,036.67 |
| MIP-1 alpha/MIP-1 beta (b) | 3,646.19 | 3,876.27 | 3,900.57 | 3,821.18 | 3,834.14 | 3,997.78 |
| MIP-3 alpha (a) | 3,893.28 | 3,971.86 | 3,994.54 | 4,037.48 | 3,870.59 | 4,249.73 |
| MIP-3 alpha (b) | 3,866.54 | 3,984.82 | 3,834.95 | 3,826.85 | 3,540.87 | 4,304.82 |
| MIP-3 beta (a) | 4,088.52 | 4,418.24 | 5,205.68 | 4,895.41 | 4,685.58 | 11,016.72 |
| MIP-3 beta (b) | 4,434.44 | 4,816.82 | 5,439 | 5,373.38 | 5,195.15 | 12,375.3 |
| MMP-9 (a) | 23,242.34 | 34,550.9 | 15,947.96 | 29,369.33 | 37,898.34 | 40,125.38 |
| MMP-9 (b) | 25,308.16 | 34,780.16 | 16,929.84 | 31,836.97 | 38,814.59 | 39,637.68 |
| Myeloperoxidase (a) | 3,970.24 | 4,069.89 | 4,524.37 | 4,204.37 | 4,671.81 | 19,131.76 |
| Myeloperoxidase (b) | 4,359.91 | 4,394.75 | 5,002.34 | 4,585.94 | 5,274.54 | 19,384.52 |
| Negative control (a) | 3,448.52 | 3,720.72 | 3,973.48 | 3,852.77 | 3,876.27 | 3,941.08 |
| Negative control (b) | 3,488.22 | 3,738.54 | 3,813.89 | 3,635.66 | 3,503.61 | 3,740.97 |
| Osteopontin (OPN) (a) | 35,660.77 | 35,127.71 | 35,876.27 | 35,597.58 | 39,423 | 41,934.39 |
| Osteopontin (OPN) (b) | 36,302.39 | 35,356.16 | 34,507.15 | 35,870.59 | 40,054.09 | 41,600.62 |
| PDGF-AA (a) | 7,590.7 | 10,172.57 | 5,582.39 | 17,538.24 | 12,287 | 8,497.23 |
| PDGF-AA (b) | 7,337.13 | 9,839.61 | 5,358.8 | 16,857.73 | 12,153.33 | 8,374.09 |
| PDGF-AB/BB (a) | 4,656.42 | 9,930.34 | 4,157.38 | 7,457.84 | 6,683.35 | 5,321.53 |
| PDGF-AB/BB (b) | 4,247.3 | 9,611.96 | 4,457.13 | 8,148.87 | 6,633.13 | 5,191.1 |
| Pentraxin-3 (a) | 6,212.67 | 4,910.8 | 6,694.7 | 7,769.73 | 6,323.66 | 11,477.68 |
| Pentraxin-3 (b) | 6,906.14 | 5,627.76 | 7,960.11 | 8,374.9 | 6,168.92 | 12,158.19 |
| PF4/CXCL4 (a) | 57,154.24 | 54,213.48 | 54,479.2 | 40,127 | 41,249.84 | 45,182.19 |
| PF4/CXCL4 (b) | 52,260.27 | 54,831.61 | 53,351.51 | 38,979.86 | 41,018.95 | 45,058.24 |
| RAGE (a) | 6,634.75 | 4,277.28 | 4,565.68 | 4,534.09 | 5,084.16 | 5,582.39 |
| RAGE (b) | 7,128.11 | 4,494.39 | 4,644.27 | 4,949.68 | 5,119.81 | 5,895.1 |
| RANTES (a) | 39,853.99 | 41,006.8 | 23,384.11 | 45,642.34 | 41,897.13 | 35,163.35 |
| RANTES (b) | 40,141.58 | 38,945.84 | 24,694.9 | 45,287.51 | 42,260.87 | 36,268.37 |
| RBP-4 (a) | 59,311.61 | 59,420.97 | 57,823.41 | 61,807.61 | 61,830.29 | 61,105.23 |
| RBP-4 (b) | 60,585.94 | 58,495.81 | 56,527.2 | 61,684.47 | 62,564.27 | 62,118.7 |
| Relaxin-2 (a) | 3,940.27 | 4,339.66 | 4,516.27 | 4,402.85 | 5,694.19 | 5,046.09 |
| Relaxin-2 (b) | 3,683.46 | 4,056.11 | 3,951.61 | 4,247.3 | 4,157.38 | 4,338.04 |
| Resistin (a) | 22,460.57 | 23,546.14 | 13,109.28 | 18,477.18 | 12,946.44 | 16,427.56 |
| Resistin (b) | 25,428.87 | 26,247.91 | 14,527 | 20,014.8 | 14,277.48 | 17,829.89 |
| Reference spot (a) | 43,270.29 | 44,483.05 | 46,708.47 | 48,631.71 | 51,555.46 | 44,853.28 |
| Reference spot (b) | 43,865.73 | 47,107.86 | 47,260.16 | 51,318.9 | 54,133.28 | 44,536.52 |
| Reference spot (c) | 40,843.96 | 43,431.51 | 44,969.94 | 47,970.65 | 47,593.94 | 46,937.73 |
| Reference spot (d) | 40,363.56 | 41,449.13 | 46,931.25 | 45,922.65 | 46,817.84 | 45,675.56 |
| Reference spot (e) | 45,060.67 | 44,535.71 | 51,301.89 | 50,129.63 | 46,112.22 | 49,145.33 |
| Reference spot (f) | 45,392.82 | 43,874.65 | 50,541.99 | 50,559.81 | 47,414.09 | 46,031.2 |
| SDF-1 alpha (a) | 12,247.3 | 9,244.16 | 11,033.73 | 14,233.73 | 13,702.29 | 19,557.08 |
| SDF-1 alpha (b) | 12,442.54 | 9,387.56 | 11,042.65 | 14,194.85 | 15,915.56 | 20,809.53 |
| Serpin E1 (a) | 36,192.22 | 23,763.25 | 36,764.97 | 36,454.7 | 25,714.04 | 38,797.58 |
| Serpin E1 (b) | 36,995.86 | 24,715.96 | 37,941.28 | 33,866.34 | 25,931.15 | 38,634.75 |
| SHBG (a) | 35,062.9 | 32,288.22 | 34,419.66 | 38,209.43 | 40,391.91 | 40,647.91 |
| SHBG (b) | 35,193.33 | 32,938.75 | 34,617.33 | 37,376.62 | 39,661.99 | 40,765.38 |
| ST2 (a) | 34,708.06 | 15,909.08 | 22,115.46 | 21,848.92 | 21,605.89 | 38,766.8 |
| ST2 (b) | 35,595.96 | 15,280.42 | 19,803.35 | 21,790.59 | 21,298.85 | 40,306.04 |
| TARC (a) | 4,385.03 | 4,347.76 | 4,249.73 | 5,221.08 | 4,581.08 | 4,813.58 |
| TARC (b) | 4,238.39 | 4,371.25 | 4,268.37 | 4,600.52 | 4,139.56 | 4,319.41 |
| TFF-3 (a) | 37,903.2 | 32,803.46 | 36,916.47 | 33,532.57 | 33,399.71 | 42,076.16 |
| TFF-3 (b) | 38,931.25 | 34,200.92 | 36,656.42 | 32,316.57 | 32,713.53 | 42,152.32 |
| TfR (a) | 8,589.58 | 6,511.61 | 9,298.44 | 8,067.05 | 10,470.7 | 13,206.49 |
| TfR (b) | 8,161.84 | 7,329.03 | 9,261.18 | 8,732.97 | 10,000.82 | 13,151.41 |
| TGF-alpha (a) | 3,949.99 | 3,910.29 | 4,101.48 | 4,034.24 | 4,338.85 | 3,990.49 |
| TGF-alpha (b) | 3,864.92 | 3,996.97 | 3,745.84 | 3,865.73 | 3,974.29 | 3,968.62 |
| Thrombospondin-1 (a) | 4,435.25 | 5,100.37 | 4,409.33 | 6,684.97 | 5,485.18 | 5,276.16 |
| Thrombospondin-1 (b) | 4,881.63 | 5,009.63 | 4,615.91 | 6,491.35 | 5,996.37 | 5,273.73 |
| TNF alpha (a) | 5,760.62 | 5,607.51 | 4,503.3 | 6,394.14 | 5,771.15 | 4,923.76 |
| TNF alpha (b) | 6,222.39 | 6,630.7 | 4,880.82 | 7,233.43 | 7,845.89 | 6,816.22 |
| uPAR (a) | 19,002.95 | 8,170.75 | 10,615.71 | 11,935.41 | 11,684.27 | 26,396.97 |
| uPAR (b) | 18,230.09 | 7,806.19 | 9,293.58 | 12,140.37 | 9,696.22 | 25,731.86 |
| VEGF (a) | 4,252.97 | 4,357.48 | 4,556.77 | 4,261.89 | 4,148.47 | 5,153.03 |
| VEGF (b) | 4,269.18 | 4,482.24 | 4,497.63 | 4,239.2 | 3,846.29 | 5,170.85 |
| Vitamin D BP (a) | 50,776.92 | 48,411.35 | 51,728.82 | 51,765.28 | 33,650.85 | 53,288.32 |
| Vitamin D BP (b) | 49,500.16 | 47,619.05 | 51,398.29 | 51,286.49 | 32,974.39 | 55,137.03 |
Note
BAFF: B cell activating factor; BDNF: brain-derived neurotrophic factor; BP: binding protein; EGF: epidermal growth factor; FGF: fibroblast growth factor; G-CSF: granulocyte-colony stimulating factor; GDF: growth differentiation factor; GM-CSF: granulocyte-macrophage colony-stimulating factor; GRO alpha: growth-regulated alpha protein; HGF: hepatocyte growth factor; ICAM-1: intercellular adhesion molecule 1; IFN: interferon; IGFBP: insulin-like growth factor-binding protein; IL: interleukin; I-TAC: interferon-inducible T cell alpha chemoattractant; LIF: leukemia inhibitory factor; MCP: monocyte chemotactic protein; M-CSF: macrophage colony-stimulating factor; MIF: macrophage migration inhibitory factor; MIP: macrophage inflammatory protein; MMP: matrix metalloproteinase; PDGF: platelet-derived growth factor; RAGE: receptor for advanced glycation endproducts; RANTES: regulated on activation, normal T cell expressed and secreted; RBP: retinol-binding protein; SDF: stromal cell-derived factor; SHBG: sex hormone–binding globulin; TARC: thymus and activation regulated chemokine; TFF: trefoil factor; TfR: transferrin receptor; TGF: transforming growth factor; TNF: tumor necrosis factor; uPAR: urokinase-type plasminogen activator receptor; VEGF: vascular endothelial growth factor.