Table 3.
P | |||||||
---|---|---|---|---|---|---|---|
Variable | BPD group (N = 20) |
Preterm no BPD group (N = 10) |
Term infants (N = 20) |
Unadjusted overall group effect | GA adjusted group effect | BW adjusted group effect | GA and BW adjusted group effect |
Heart rate, beats/min | 146 ± 10 | 152 ± 11 | 145 ± 8 | 0.24 | 0.2 | 0.13 | 0.44 |
Diastolic parameter: | |||||||
EDT, ms | 75.6 ± 7.9 | 63.6 ± 8.2 | 60.5 ± 7 | <0.0001 | 0.001 | 0.001 | 0.001a |
ESWS, g/cm2 | 72 ± 10.8 | 44.2 ± 6.5 | 41.8 ± 6.4 | <0.0001 | <0.0001 | <0.0001 | <0.0001b |
E/A | 1.07 ± 0.07 | 0.91 ± 0.04 | 0.89 ± 0.09 | <0.0001 | <0.0001 | <0.0001 | <0.0001b |
IVRT, ms | 68.8 ± 3.9 | 58.5 ± 7.8 | 54.2 ± 5.7 | <0.0001 | <0.0001 | <0.0001 | <0.0001a |
MVSV, mL/kg | 4.7 ± 0.7 | 5.6 ± 0.6 | 5.9 ± 0.1 | <0.0001 | 0.01 | <0.0001 | 0.002b |
PV VTI, cm | 5.4 ± 1.8 | 7.8 ± 0.9 | 8.2 ± 1.3 | <0.0001 | <0.0001 | <0.0001 | <0.0001a |
Tei index | 0.33 ± 0.05 | 0.28 ± 0.01 | 0.27 ± 0.05 | 0.001 | 0.03 | 0.004 | 0.03a |
Systolic parameter: | |||||||
mVCFc | 1.7 ± 0.4 | 2.7 ± 0.2 | 3 ± 0.6 | <0.0001 | <0.0001 | <0.0001 | <0.0001a |
LVSV, mL/kg | 1.25 ± 0.32 | 1.29 ± 0.09 | 1.32 ± 0.21 | 0.72 | 0.03 | 0.48 | 0.046 |
LVO, mL/kg/min | 183 ± 45 | 189 ± 9 | 191 ± 32 | 0.75 | 0.054 | 0.21 | 0.03 |
FS, % | 33.1 ± 3.3 | 33.3 ± 2.8 | 33.5 ± 0.5 | 0.96 | 0.95 | 0.93 | 0.92 |
LVPW, mm | 1.98 ± 0.13 | 4.1 ± .19 | 5.8 ± 0.13 | <0.0001 | <0.0001 | <0.0001 | <0.0001a |
Data are presented as mean ± standard deviation. BPD: bronchopulmonary dysplasia; EDT: E wave deceleration time; ESWS: end-systolic wall stress; FS: fractional shortening; IVRT: end-systolic wall stress; LVO: left ventricular output; LVPW: left ventricular posterior wall; LVSV: left ventricular stroke volume; mVCFc: mean velocity of circumferential fiber shortening; MVSV: mitral valve stroke volume; PV VTI: pulmonary vein velocity time integral.
BPD group versus No BPD group is significant (P < 0.05).
BPD group versus No BPD group and BPD group versus Term controls are significant (P < 0.05).