Table 1.
Genes identified in the translatome of healthy mouse kidney pericytes that affect vascular permeability, tone, and homeostasis
| Gene Symbol | Gene Name |
|---|---|
| Basement membrane | |
| COL4A1 | Collagen, type IV, α1 |
| COL4A2 | Collagen, type IV, α2 |
| COL4A4 | Collagen, type IV, α4 |
| DAG1 | Dystroglycan 1 |
| NID1 | Nidogen 1 |
| HSPG2 | Heparan sulfate proteoglycan 2 |
| ITGB8 | Integrin, β8 |
| ITGA3 | Integrin, α3 |
| ITGAL | Integrin, αL |
| ITGA5 | Integrin, α5 |
| ITGB5 | Integrin, β5 |
| ITGA1 | Integrin, α1 |
| ITGB1 | Integrin, β1 |
| ITGA6 | Integrin, α6 |
| ITGA8 | Integrin, α8 |
| ITGB8 | Integrin, β8 |
| LAMC1 | Laminin, γ1 |
| LAMA4 | Integrin, α4 |
| LAMA5 | Integrin, α5 |
| LAMA3 | Integrin, α3 |
| LAMB3 | Integrin, β3 |
| LAMC3 | Laminin, γ3 |
| LAMB1 | Integrin, β1 |
| LAMA1 | Integrin, α1 |
| LAMC2 | Laminin, γ2 |
| Vascular tone | |
| AGT | Angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| GDF15 | Growth differentiation factor 15 |
| GMFB | Glia maturation factor-β |
| FGF2 | Fibroblast growth factor 2 (basic) |
| PGF | Placental growth factor |
| CMTM7 | CKLF-like MARVEL transmembrane domain containing 7 |
| EDN1 | Endothelin 1 |
| IL1B | Interleukin 1β |
| IL1RN | Interleukin 1 receptor antagonist |
| MIF | Macrophage migration inhibitory factor (glycosylation-inhibiting factor) |
| TGFB1 | Transforming growth factor-β1 |
| PF4 | Platelet factor 4 |
| SCG2 | Secretogranin II |
| TNFSF10 | Tumor necrosis factor (ligand) superfamily, member 10 |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| Vascular homeostasis | |
| ANGPT1 | Angiopoietin 1 |
| ANGPT2 | Angiopoietin 2 |
| ANGPT4 | Angiopoietin 4 |
| ANGPTL3 | Angiopoietin-like 3 |
| BDNF | Brain-derived neurotrophic factor |
| BMP2 | Bone morphogenetic protein 2 |
| BMP4 | Bone morphogenetic protein 4 |
| BMP6 | Bone morphogenetic protein 6 |
| BTC | β-Cellulin |
| CTGF | Connective tissue growth factor |
| EGF | Epidermal growth factor |
| EREG | Epiregulin |
| FGF1 | Fibroblast growth factor 1 (acidic) |
| FGF2 | Fibroblast growth factor 2 (basic) |
| FGF3 | Fibroblast growth factor 3 |
| FGF4 | Fibroblast growth factor 4 |
| FGF7 | Fibroblast growth factor 7 |
| FGF9 | Fibroblast growth factor 9 |
| FGF18 | Fibroblast growth factor 18 |
| FIGF | c-Fos-induced growth factor (vascular endothelial growth factor D) |
| GAS6 | Growth arrest-specific 6 |
| GDNF | Glial cell-derived neurotrophic factor |
| GHRL | Ghrelin/obestatin prepropeptide |
| GRN | Granulin |
| HBEGF | Heparin-binding EGF-like growth factor |
| HGF | Hepatocyte growth factor (hepapoietin A, scatter factor) |
| IGF1 | Insulin-like growth factor 1 (somatomedin C) |
| IGF2 | Insulin-like growth factor 2 |
| INHBA | Inhibin-βA |
| JAG1 | Jagged 1 |
| KITLG | KIT ligand |
| LEFTY1 | Left-right determination factor 1 |
| LEP | Leptin |
| MDK | Midkine (neurite growth-promoting factor 2) |
| NDP | Norrie disease (pseudoglioma) |
| NGF | Nerve growth factor (β-polypeptide) |
| NODAL | Nodal growth differentiation factor |
| NRG2 | Neuregulin 2 |
| PDGFA | Platelet-derived growth factor α-polypeptide |
| PDGFB | Platelet-derived growth factor β-polypeptide |
| PDGFC | Platelet-derived growth factor C |
| PGF | Placental growth factor |
| PTN | Pleiotrophin |
| Vascular homeostasis | |
| TGFA | Transforming growth factor-α |
| TGFB1 | Transforming growth factor-β1 |
| TGFB2 | Transforming growth factor-β2 |
| VEGFA | Vascular endothelial growth factor A |
| VEGFB | Vascular endothelial growth factor B |
| VEGFC | Vascular endothelial growth factor C |
| AIMP1 | Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 |
| CCL2 | Chemokine (C-C motif) ligand 2 |
| CCL5 | Chemokine (C-C motif) ligand 5 |
| CCL11 | Chemokine (C-C motif) ligand 11 |
| CCL28 | Chemokine (C-C motif) ligand 28 |
| CSF1 | Colony stimulating factor 1 (macrophage) |
| CSF3 | Colony stimulating factor 3 (granulocyte) |
| CX3CL1 | Chemokine (C-X3-C motif) ligand 1 |
| CXCL2 | Chemokine (C-X-C motif) ligand 2 |
| CXCL6 | Chemokine (C-X-C motif) ligand 6 |
| CXCL10 | Chemokine (C-X-C motif) ligand 10 |
| CXCL12 | Chemokine (C-X-C motif) ligand 12 |
| CXCL14 | Chemokine (C-X-C motif) ligand 14 |
| Cxcl15 | Chemokine (C-X-C motif) ligand 15 |
| EDN1 | Endothelin 1 |
| IL6 | Interleukin 6 |
| IL13 | Interleukin 13 |
| IL15 | Interleukin 15 |
| IL18 | Interleukin 18 |
| IL17B | Interleukin 17B |
| IL1B | Interleukin 1β |
| IL1RN | Interleukin 1 receptor antagonist |
| LIF | Leukemia inhibitory factor |
| PF4 | Platelet factor 4 |
| SLURP1 | Secreted LY6/PLAUR domain containing 1 |
| SPP1 | Secreted phosphoprotein 1 |
| TIMP1 | Tissue inhibitor of metallopeptidase 1 |
| TNF | Tumor necrosis factor |
| TNFSF10 | Tumor necrosis factor (ligand) superfamily, member 10 |
| TNFSF12 | Tumor necrosis factor (ligand) superfamily, member 12 |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| WNT2 | Wingless-type MMTV integration site family member 2 |
| WNT4 | Wingless-type MMTV integration site family, member 4 |
| WNT5A | Wingless-type MMTV integration site family, member 5A |
| WNT7A | Wingless-type MMTV integration site family, member 7A |