Figure 2.

Mice infected with Plasmodium berghei K173 develop a severe anemia. RBC count (A), hemoglobin concentration (B) and hematocrit (C) decreased dramatically from day 7 to day 18. Conversely, MCV was increased 13 to 18 days after infection with PbK. Data shown are mean ± sem and were compared for each time point to values for control mice at t=0 (n=5 to 10 mice per group except at day 18 where only 3 mice had survived) by one-way ANOVA. ***P<0.001, **P<0.01, *P<0.05. RBC: red blood cell; PbK: Plasmodium berghei K173; MCV: mean corpuscular volume.