Table 2.
DNA and RNA metabolism-related biological processes in response to x-ray exposure
| Term | X4d1_UP | X4d1_DN | X4d7_UP | X4d7_DN | |
|---|---|---|---|---|---|
| GO:0006259 | DNA metabolic process | - | 3.80E-10 | - | - |
| GO:0016071 | mRNA metabolic process | - | 4.06E-10 | - | - |
| GO:0006396 | RNA processing | - | 4.40E-10 | - | - |
| GO:0006397 | mRNA processing | - | 5.67E-10 | - | - |
| GO:0006412 | translation | - | 7.39E-10 | - | - |
| GO:0006260 | DNA replication | - | 0.0003 | - | - |
| GO:0010629 | negative regulation of gene expression | - | 0.0136 | - | - |
| GO:0006261 | DNA-dependent DNA replication | - | 0.0181 | - | - |
| GO:0006310 | DNA recombination | - | 0.0271 | - | - |
| GO:0040029 | regulation of gene expression, epigenetic | - | 0.0382 | - | - |
| GO:0042127 | regulation of cell proliferation | - | 0.0396 | - | 0.0097 |
Significantly enriched biological processes among genes downregulated in response to 1 and 4 Gy x-ray irradiation at days 1 and 7. Benjamini-corrected p values are shown. Processes unique to x-rays are in bold. X4d1: 4 Gy X-rays, day 1; X4d7: 4 Gy X-rays, day 7. UP, upregulated; DN: downregulated