Table 3.
DNA and RNA-metabolism related biological processes in response to neutron exposure
| Term | N1d1_UP | N1d1_DN | N1d7_UP | N1d7_DN | |
|---|---|---|---|---|---|
| GO:0006396 | RNA processing | - | - | - | 3.27E-18 |
| GO:0050658 | RNA transport | - | - | - | 3.35E-06 |
| GO:0000956 | nuclear-transcribed mRNA catabolic process | - | - | - | 0.0204 |
| GO:0006260 | DNA replication | - | 9.59E-06 | - | 2.17E-06 |
| GO:0006399 | tRNA metabolic process | - | - | - | 1.38E-06 |
| GO:0006412 | translation | - | 0.0002 | - | 4.55E-11 |
| GO:0008380 | RNA splicing | - | 0.0097 | - | 3.21E-13 |
| GO:0034660 | ncRNA metabolic process | - | - | - | 2.23E-05 |
| GO:0016071 | mRNA metabolic process | - | 0.0145 | - | 9.63E-14 |
| GO:0006259 | DNA metabolic process | - | 2.06E-13 | - | 3.11E-11 |
| GO:0006403 | RNA localization | - | - | - | 1.52E-06 |
| GO:0045892 | negative regulation of transcription, DNA-templated | - | 0.0119 | - | - |
| GO:0016444 | somatic cell DNA recombination | - | 0.0034 | - | - |
| GO:0006401 | RNA catabolic process | - | - | - | 0.0427 |
| GO:0016458 | gene silencing | - | - | - | 0.0358 |
| GO:0006310 | DNA recombination | - | 0.0027 | - | 4.15E-05 |
| GO:0051052 | regulation of DNA metabolic process | - | - | - | 0.0047 |
Significantly enriched biological processes among genes downregulated in response to 1 Gy neutron irradiation at days 1 and 7. Benjamini-corrected p values are shown. Processes unique to neutrons are in bold. N1d1: 1 Gy neutron, day 1; N1d7: 1 Gy neutron, day 7. UP, upregulated; DN: downregulated