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. 2017 Jan 3;15:1. doi: 10.1186/s12951-016-0241-6

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Quantification of the cellular uptake of PHBV nanoparticles. Concentration dependency. To evaluate concentration dependency in the cellular uptake of NPs, HeLa (a), SKOV-3 (b) and PBMC (c) were incubated with a PHBV-RN solution at different concentrations (1, 10, 100, 500 and 1000 µg/mL) for 2 h. d Mean fluorescence intensity analysis of the three different cells. Mean fluorescence intensity was determined through flow cytometry (n = 3)