Table 4.
Cox proportional hazard model of baseline biochemical risk factors for the development of major adverse cardiovascular events stratified by acute coronary syndrome and elective PCI subjects
| Acute coronary syndrome | Elective PCI | |||||||
|---|---|---|---|---|---|---|---|---|
| Baseline data | Univariate analysis HR (95% CI) |
P value | Multivariate model HR (95% CI) | P-value | Univariate analysis HR (95% CI) |
P value | Multivariate model HR (95% CI) | P value |
| Body mass index | 0.98 (0.95–1.01) | 0.135 | 0.99 (0.97–1.03) | 0.942 | ||||
| Waist circumference | 1.01 (0.99–1.02) | 0.131 | 1.01 (0.99–1.02) | 0.172 | ||||
| Waist to hip ratio | 3.45 (1.30–7.40) | 0.016 | 3.56 (1.29–7.03) | 0.019 | ||||
| Systolic BP | 0.99 (0.99–1.00) | 0.701 | 1.01 (0.99–1.01) | 0.146 | ||||
| Diastolic BP | 0.24 (0.07–0.90) | 0.034 | 0.15 (0.02–0.97) | 0.046 | ||||
| HbA1C | 1.06 (0.99–1.11) | 0.063 | 1.06 (0.99–1.16) | 0.192 | ||||
| Fasting glucose | 3.98 (2.24–6.98) | <0.0001 | 3.82 (1.85–7.66) | 0.0004 | ||||
| Total cholesterol | 0.43 (0.24–0.91) | 0.030 | 1.04 (0.30–3.61) | 0.946 | ||||
| Triglyceride | 0.99 (0.99–1.00) | 0.121 | 0.99 (0.99–1.00) | 0.154 | ||||
| HDL-cholesterol | 0.29 (0.11–0.77) | 0.014 | 0.30 (0.11–0.83) | 0.021 | ||||
| LDL-cholesterol | 1.00 (0.99–1.00) | 0.447 | 1.00 (0.99–1.01) | 0.221 | ||||
| Uric acid | 1.00 (0.96–1.03) | 0.981 | 1.17 (1.09–1.26) | <0.0001 | 1.14 (1.01–1.28) | 0.041 | ||
| Creatinine | 1.10 (1.03–1.16) | 0.005 | 1.09 (1.05–1.13) | 0.0004 | ||||
| eGFR | 0.46 (0.32–0.66) | 0.0001 | 0.20 (0.05–0.86) | 0.031 | 0.32 (0.23–0.48) | <0.0001 | ||
| Hs–CRP | 1.00 (0.99–1.01) | 0.713 | 1.01 (1.00–1.01) | 0.013 | ||||
| White blood cell | 1.02 (0.99–1.05) | 0.148 | 1.01 (0.97–1.05) | 0.653 | ||||
| Red blood cell | 0.84 (0.73–0.97) | 0.017 | 0.88 (0.73–1.04) | 0.158 | ||||
| Hemoglobin | 0.93 (0.89–0.98) | 0.004 | 0.95 (0.89–1.02) | 0.143 | ||||
| Hematocrit | 0.98 (0.96–0.99) | 0.003 | 0.98 (0.95–1.00) | 0.073 | ||||
| MCV | 1.00 (0.98–1.01) | 0.656 | 1.02 (1.00–1.04) | 0.047 | ||||
| MCH | 0.97 (0.94–1.01) | 0.099 | 1.00 (0.97–1.01) | 0.687 | ||||
| MCHC | 0.91 (0.84–0.99) | 0.029 | 0.89 (0.81–0.98) | 0.016 | ||||
PCI, percutaneous coronary intervention; HR, hazard ratio; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular-hemoglobin concentration. eGFR = estimated glomerular filtration rate calculated by the chronic kidney disease-EPI two-level race equation [12]