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. 2016 Nov 16;5(11):e004255. doi: 10.1161/JAHA.116.004255

Table 4.

Change in Creatine Kinase–Myocardial Band at 16 and 24 Hours After PCI in Patients With Short and Long Time Intervals Between Study Drug Infusion and PCI

Short (Less Than Median) Time Interval Long (Greater Than Median) Time Interval
Placebo Inclacumab (5 mg/kg) Inclacumab (20 mg/kg) Placebo Inclacumab (5 mg/kg) Inclacumab (20 mg/kg)
Baseline GM (IQR) 10.76 (3.95–30.00) 7.41 (2.40, 21.65) 7.99 (2.75–17.85) 8.37 (3.20–21.30) 7.68 (3.30–12.90) 7.71 (3.30–14.50)
16 hours after PCI GM 10.96 (n=56) 8.36 (n=48) 7.10 (n=54) 8.40 (n=58) 7.50 (n=46) 7.33 (n=53)
Adjusted GM percent change from baseline to 16 hours 31.0 24.6 −3.0 12.8 5.8 1.8
Placebo‐adjusted GM percent change at 16 hours −4.9 −26.0 −6.2 −9.8
95% CI −30.0 to 29.2 −45.1 to −0.2 −30.9 to 27.3 −33.0 to 21.3
P value 0.75 0.049 0.68 0.49
24 hours after PCI GM 8.99 (n=50) 6.96 (n=45) 5.56 (n=52) 7.30 (n=54) 6.22 (n=47) 6.02 (n=49)
Adjusted GM percent change from baseline to 24 hours 26.6 16.5 −12.3 12.2 1.4 −5.4
Placebo‐adjusted GM percent change at 24 hours −8.0 −30.7 −9.6 −15.7
95% CI −32.1 to 24.7 −48.4 to −7.0 −32.6 to 21.2 −37.0 to 12.9
P value 0.59 0.01 0.50 0.25

GM indicates geometric mean; IQR, interquartile range; PCI, percutaneous coronary intervention.